Tag: tamoxifen SSRIs
Tamoxifen and SSRIs: What You Need to Know About Drug Interactions and Breast Cancer Outcomes
Tamoxifen relies on CYP2D6 to form its active metabolite, endoxifen. Some SSRIs block this enzyme, potentially lowering endoxifen levels. But large clinical studies show this doesn't reliably increase cancer recurrence risk. Learn which antidepressants are safest and what experts really recommend.