Tag: tricyclic antidepressants

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks

Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of cognitive decline and heart rhythm problems-especially in older adults. Learn why these drugs are being phased out and what safer options exist.

Tricyclic Antidepressant Side Effects: Amitriptyline, Nortriptyline, and Other TCAs Explained

Tricyclic Antidepressant Side Effects: Amitriptyline, Nortriptyline, and Other TCAs Explained

Tricyclic antidepressants like amitriptyline and nortriptyline still help with chronic pain and treatment-resistant depression-but their side effects can be severe. Learn the real risks, who should avoid them, and how to use them safely.